The PTPN14 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to protein tyrosine phosphatase non-receptor type 14, and PTPN14. This antibody recognizes Human antigen. The PTPN14 Antibody has been validated for the following applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, and Western Blot.
Description
Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor